2 definitions found From The Collaborative International Dictionary of English v.0.48 [gcide]: moleskin \mole"skin`\ (m[=o]l"sk[i^]n), n. 1. Any fabric having a thick soft shag, like the fur of a mole; esp., a kind of strong twilled fustian. [1913 Webster] 2. A soft fabric having an adhesive backing, applied to the skin at points susceptible to abrasion, as on the feet, to prevent irritation or blistering during exercise, such as hiking. [PJC] From WordNet (r) 2.0 [wn]: moleskin n : a durable cotton fabric with a velvety nap
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