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2 definitions found From The Collaborative International Dictionary of English v.0.48 [gcide]: manic-depressive \manic-depressive\ n. (Med.), A person suffering from {manic-depressive psychosis}. [PJC] From WordNet (r) 2.0 [wn]: manic-depressive adj : suffering from a disorder characterized by alternating mania and depression n : a person afflicted with manic-depressive illness
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