Immunotolerance

1 definition found

From The Collaborative International Dictionary of English v.0.48 [gcide]:

  Tolerance \Tol"er*ance\, n. [L. tolerantia: cf. F.
     tol['e]rance.]
     1. The power or capacity of enduring; the act of enduring;
        endurance.
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              Diogenes, one frosty morning, came into the market
              place, shaking, to show his tolerance. --Bacon.
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     2. The endurance of the presence or actions of objectionable
        persons, or of the expression of offensive opinions;
        toleration.
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     3. (Med.) The power possessed or acquired by some persons of
        bearing doses of medicine which in ordinary cases would
        prove injurious or fatal.
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     4. (Forestry) Capability of growth in more or less shade.
        [Webster 1913 Suppl.]
  
     5. the allowed amount of variation from the standard or from
        exact conformity to the specified dimensions, weight,
        hardness, voltage etc., in various mechanical or
        electrical devices or operations; -- caklled also
        {allowance} specif.: (Coinage) The amount which coins,
        either singly or in lots, are legally allowed to vary
        above or below the standard of weight or fineness.
        [Webster 1913 Suppl. +PJC]
  
     6. (Biochemistry) the capacity to resist the deleterious
        action of a chemical agent normally harmful to the
        organism; as, the acquired tolerance of bacteria to
        anitbiotics.
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     7. (Immunology) the acquired inability to respond with an
        immune reaction to an antigen to which the organism
        normally responds; -- called also {immunotolerance},
        {immunological tolerance}, or {immune tolerance}. Such
        tolerance may be induced by exposing an animal to the
        antigen at a very early stage of life, prior to maturation
        of the immune system, or, in adults, by exposing the
        animal to repeated low doses of a weak protein antigen
        ({low-zone tolerance}), or to a large amount of an antigen
        ({high-zone tolerance}).
        [PJC]
  
     {Tolerance of the mint}. (Coinage) Same as {Remedy of the
        mint}. See under {Remedy}.
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