Vioxx

3 definitions found

From The Collaborative International Dictionary of English v.0.48 [gcide]:

  rofecoxib \rofecoxib\ (Chem. & Med.)
     A chemical substance ({C17H14O4S}, molecular weight 314.36)
     used in medicine as an analgesic to alleviate pain and
     inflammation; it is a synthetic compound, and is marketed by
     Merck & Co. under the trade name {Vioxx}, in tablets giving
     dosages of 12.5 or 25 milligrams. It is classed as a


     non-steroidal anti-inflammatory drug (NSAID). Chemically, it
     is 4-[4-(methylsulfony)phenyl]-3-phenyl-2(5H) furanone. Its
     chemical structure contains two phenyl rings and a furanone
     ring. It is believed to act by inhibition of prostaglandin
     biosynthesis, through inhibition of the enzyme
     cyclooxygenase-2 (COX-2); unlike {aspirin}, it does not
     inhibit cyclooxygenase-1.
     [PJC]

From The Collaborative International Dictionary of English v.0.48 [gcide]:

  VIOXX \VI`OXX\ (v[imac]"[o^]ks), prop. n. [Trade name, used by
     Merck & Co.] (Chem. & Med.)
     A trade name for {rofecoxib}. [Trade name]
     [PJC]

From WordNet (r) 2.0 [wn]:

  Vioxx
       n : a Cox-2 inhibitor (trade name Vioxx) that relieves pain
           without harming the digestive tract [syn: {rofecoxib}]