1 definition found From The Collaborative International Dictionary of English v.0.48 [gcide]: Sextodecimo \Sex`to*dec"imo\, n.; pl. {Sextodecimos}. A book composed of sheets each of which is folded into sixteen leaves; hence, indicating, more or less definitely, a size of a book; -- usually written 16mo, or 16[deg]. [1913 Webster]
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