2 definitions found From The Collaborative International Dictionary of English v.0.48 [gcide]: Scleroderma \Scler`o*der"ma\, n. [NL.] (Med.) A disease of adults, characterized by a diffuse rigidity and hardness of the skin. [1913 Webster] From WordNet (r) 2.0 [wn]: scleroderma n 1: an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin [syn: {dermatosclerosis}] 2: genus of poisonous fungi having hard-skinned fruiting bodies: false truffles [syn: {genus Scleroderma}]
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