1 definition found From The Collaborative International Dictionary of English v.0.48 [gcide]: Opisthodome \O*pis"tho*dome\, n. [L. opisthodomus, Gr. ?; 'o`pisqen behind + do`mos house: cf. F. opisthodome.] (Arch.) A back chamber; especially, that part of the naos, or cella, farthest from the main entrance, sometimes having an entrance of its own, and often used as a treasury. [1913 Webster]
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