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2 definitions found From The Collaborative International Dictionary of English v.0.48 [gcide]: Macroglossia \Mac`ro*glos"si*a\, n. [NL. See {Macro-}, and {Glossa}.] (Med.) Enlargement or hypertrophy of the tongue. [1913 Webster] From WordNet (r) 2.0 [wn]: macroglossia n : a congenital disorder characterized by an abnormally large tongue; often seen in cases of Down's syndrome
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