2 definitions found From The Collaborative International Dictionary of English v.0.48 [gcide]: Issus \Issus\ prop. n. A battle (333 BC) in which Alexander the Great defeated the Persians under Darius III. Syn: battle of Issus. [WordNet 1.5] From WordNet (r) 2.0 [wn]: Issus n : a battle (333 BC) in which Alexander the Great defeated the Persians under Darius III [syn: {battle of Issus}]
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