1 definition found From The Collaborative International Dictionary of English v.0.48 [gcide]: Frustule \Frus"tule\, n. [L. frustulum, dim. fr. frustum a piece: cf. F. frustule.] (Bot.) The siliceous shell of a diatom. It is composed of two valves, one overlapping the other, like a pill box and its cover. [1913 Webster]
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