1 definition found From The Collaborative International Dictionary of English v.0.48 [gcide]: Coloboma \Col`o*bo"ma\, n. [NL. fr. Gr. ?, the part taken away in mutilation, fr. ? to mutilate.] (Anat. & Med.) A defect or malformation; esp., a fissure of the iris supposed to be a persistent embryonic cleft. [Webster 1913 Suppl.]
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